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Product Name | Complement Component 8, gamma Polypeptide (C8G) (AA 21-202) protein (His tag) |
Description | Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections. Synonyms: Complement component C8 gamma chain,C8G |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | C8C |
Gene, Accession, CAS # | Gene ID: 733 |
Catalog # | ABIN2115312 |
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Order / More Info | Complement Component 8, gamma Polypeptide (C8G) (AA 21-202) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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