| 产品详情 |
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| Antigenic Specificity | Phospho-Tau (Ser199) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Functional Assay: Assay Dependent, Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-Tau (Ser199) Polyclonal Antibody. Tau is a neuronal microtubule-associated protein found predominantly on axons. The function of Tau is to promote tubulin polymerization and stabilize microtubules. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization. In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the bu |
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| Immunogen | n/a |
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| Other Names | MAPT, Microtubule-associated protein tau, MTBT1, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau |
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| Gene, Accession # | Entrez: 17762, 29477, 4137; Uniprot: P10636, P10637, P19332 |
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| Catalog # | 44-734G |
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| Price | |
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| Order / More Info | Phospho-Tau (Ser199) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 15546861, 18946722, 19183272, 20651003, 22083255, 22249463, 22361619, 23020770, 23560093, 23705847, 24754737, 24788298, 24887203, 25219467, 25663420, 26239295, 26458742, 26511732, 26857506, 27567836 |
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