产品详情 |
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Antigenic Specificity | Phospho-TCF3 (Thr355) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-TCF3 (Thr355) Polyclonal Antibody. E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described. |
Immunogen | n/a |
Other Names | E2A, E47, ITF1, TCF-3, VDIR, bHLHb21, VDR interacting repressor, class B basic helix-loop-helix protein 21, helix-loop-helix protein HE47, immunoglobulin transcription factor 1, kappa-E2-binding factor, negative vitamin D response element-binding protein, transcription factor E2-alpha, transcription |
Gene, Accession # | Entrez: 171046, 21423, 6929; Uniprot: P15806, P15923, P21677 |
Catalog # | PA5-37753 |
Price | |
Order / More Info | Phospho-TCF3 (Thr355) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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