产品详情 |
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Antigenic Specificity | Phospho-TEK (Tyr1113) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Dot blot: 1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-TEK (Tyr1113) Polyclonal Antibody. The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. |
Immunogen | n/a |
Other Names | TEKT1; Tektin-1 |
Gene, Accession # | Entrez: 7010; Uniprot: Q02763 |
Catalog # | PA5-12992 |
Price | |
Order / More Info | Phospho-TEK (Tyr1113) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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