产品详情 |
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Antigenic Specificity | ICAM-1 |
Clone | 1H4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ICAM-1 Monoclonal Antibody (1H4), PE. CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. |
Immunogen | n/a |
Other Names | BB2, P3.58, ICAM-1, cell surface glycoprotein P3.58, intercellular adhesion molecule 1, human rhinovirus receptor, major group rhinovirus receptor |
Gene, Accession # | Entrez: 3383; Uniprot: P05362 |
Catalog # | MA1-19663 |
Price | |
Order / More Info | ICAM-1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20336056, 21384185 |
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