| 产品详情 |
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| Antigenic Specificity | ICAM-1 |
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| Clone | MEM-111 |
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| Host Species | Mouse |
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| Reactive Species | bovine, human, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Flow Cytometry: 2 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ICAM-1 Monoclonal Antibody (MEM-111). CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. |
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| Immunogen | n/a |
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| Other Names | BB2, P3.58, ICAM-1, cell surface glycoprotein P3.58, intercellular adhesion molecule 1, human rhinovirus receptor, major group rhinovirus receptor |
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| Gene, Accession # | Entrez: 25464, 281839, 3383; Uniprot: P05362, Q00238, Q95132 |
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| Catalog # | MA1-19123 |
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| Price | |
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| Order / More Info | ICAM-1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11500459, 16234238, 17050074, 18056355, 20070238, 27998726 |
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