产品详情 |
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Antigenic Specificity | USP6NL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | USP6NL Polyclonal Antibody. GTPase-activating proteins(GAPs) accelerate the intrinsicrate of GTP hydroysis of Ras-related proteins, resulting in downregulation of their active form.RN-tre (related to the N-terminus of tre), also known as USP6NL(USP6 Nterminal like) or TRE2NL, is an 828 amino acid protein thatcontains one RabGAP TBC domain. Expressed in awide variety of tissues, RN-tre functions as a GTPase-activating protein for Rab 5A and isthought to be involved in receptor trafficking, aswell asin the inhibition of EGFR internalization. In response to DNA damage, RN-tre may be phosphorylated by ATM or ATR. The gene encoding RN-tre mapsto human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. |
Immunogen | n/a |
Other Names | USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre; USP6NL; KIAA0019 |
Gene, Accession # | Entrez: 291309, 9712, 98910; Uniprot: Q80XC3, Q92738 |
Catalog # | PA5-75944 |
Price | |
Order / More Info | USP6NL Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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