产品详情 |
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Antigenic Specificity | ARPP19 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ARPP19 Polyclonal Antibody. Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA (By similarity). |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 10776, 59046, 60336; Uniprot: P56211, P56212, Q712U5 |
Catalog # | PA5-68127 |
Price | |
Order / More Info | ARPP19 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
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