| 产品详情 |
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| Antigenic Specificity | DMTN |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 20 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DMTN Polyclonal Antibody. The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis diseas |
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| Immunogen | n/a |
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| Other Names | Dematin actin-binding protein, DMT, EPB49, Erythrocyte membrane protein band 4.9, erythrocyte membrane protein band 4.9 (dematin) |
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| Gene, Accession # | Entrez: 2039; Uniprot: Q08495 |
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| Catalog # | A305-518A-T |
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| Price | |
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| Order / More Info | DMTN Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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