| 产品详情 |
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| Antigenic Specificity | GADD34 |
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| Clone | OTI3D12 |
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| Host Species | Mouse |
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| Reactive Species | canine, human, mouse, nonhuman primate, rat |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GADD34 Monoclonal Antibody (OTI3D12). Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. |
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| Immunogen | n/a |
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| Other Names | GADD34, growth arrest and DNA damage-inducible protein GADD34, growth arrest and DNA-damage-inducible 34, myeloid differentiation primary response protein MyD116 homolog, protein phosphatase 1 regulatory subunit 15A, protein phosphatase 1, regulatory (inhibitor) subu |
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| Gene, Accession # | Entrez: 171071, 17872, 23645, 476419, 718350; Uniprot: O75807, P17564, Q6IN02 |
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| Catalog # | MA5-25874 |
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| Price | |
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| Order / More Info | GADD34 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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