产品详情 |
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Antigenic Specificity | GADD34 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1:50-1:100, Immunofluorescence: 1:50 - 1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GADD34 Polyclonal Antibody. Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. |
Immunogen | n/a |
Other Names | PPP1R15A, PR15A, Protein phosphatase 1 regulatory subunit 15A, Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog |
Gene, Accession # | Entrez: 17872, 23645; Uniprot: O75807, P17564 |
Catalog # | PA1-139 |
Price | |
Order / More Info | GADD34 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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