产品详情 |
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Antigenic Specificity | GADD45A |
Clone | D.81.E |
Host Species | Rabbit |
Reactive Species | human, mouse, nonhuman primate, rat |
Isotype | IgG |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GADD45A Monoclonal Antibody (D.81.E). GADD45 alpha, beta and gamma are an evolutionarily conserved, homologous family of nuclear proteins that function as stress sensors for cellular physiological and environmental damage. GADD45 proteins are required for the activation of the G2/M checkpoint induced by UV radiation or alkylating agents. GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase. GADD45 forms a complex with p21 and Cdc2, and may serve as core for interaction with other cell cycle regulators. |
Immunogen | n/a |
Other Names | DDIT1; GADD45 |
Gene, Accession # | Entrez: 13197, 1647, 25112; Uniprot: P24522, P48316, P48317 |
Catalog # | MA5-17014 |
Price | |
Order / More Info | GADD45A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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