产品详情 |
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Antigenic Specificity | Phospho-GluR2 (Tyr876) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-GluR2 (Tyr876) Polyclonal Antibody. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and |
Immunogen | n/a |
Other Names | AMPA-selective glutamate receptor 2; OTTHUMP00000165324; OTTHUMP00000220942; OTTHUMP00000220943; gluR-2; gluR-B; glutamate receptor 2 |
Gene, Accession # | Entrez: 14800, 2891, 29627; Uniprot: P19491, P23819, P42262 |
Catalog # | PA5-17096 |
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Order / More Info | Phospho-GluR2 (Tyr876) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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