产品详情 |
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Antigenic Specificity | Phospho-GP130 (Tyr759) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-GP130 (Tyr759) Polyclonal Antibody. The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding |
Immunogen | n/a |
Other Names | GP130-RAPS |
Gene, Accession # | Entrez: 25205, 3572; Uniprot: P40189, P40190 |
Catalog # | PA5-64830 |
Price | |
Order / More Info | Phospho-GP130 (Tyr759) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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