产品详情 |
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Antigenic Specificity | Phospho-GRB2 (Ser159) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-GRB2 (Ser159) Polyclonal Antibody. GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2 - Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signalling pathway. |
Immunogen | n/a |
Other Names | ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2, HT027, SH2/SH3 adapter GRB2, abundant SRC homology, epidermal growth factor receptor-binding protein GRB2, growth factor receptor-bound protein 3 |
Gene, Accession # | Entrez: 14784, 2885, 81504; Uniprot: P62993, P62994, Q60631 |
Catalog # | PA5-37587 |
Price | |
Order / More Info | Phospho-GRB2 (Ser159) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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