| 产品详情 |
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| Antigenic Specificity | Phospho-GRK1 (Ser21) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-GRK1 (Ser21) Polyclonal Antibody. The sensation of sight is the result of a cascade of events starting with the interaction of photoactivated rhodopsin with a protein called transducin. Rhodopsin kinase is a G-protein-coupled Ser/Thr kinase, also known as GRK1, which is a key element in the regulation of this cascade. Following phosphorylation by GRK1, arrestin is recruited to phospho-rhodopsin quenching its phototransductive activity by preventing further interaction with transducin. By breaking the cycle of phototransduction, GRK1 plays an important role in the restoration of the system for subsequent visual events. |
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| Immunogen | n/a |
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| Other Names | Rhodopsin kinase |
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| Gene, Accession # | Entrez: 24013, 6011, 81760; Uniprot: Q15835, Q63651, Q9WVL4 |
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| Catalog # | PA5-38496 |
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| Price | |
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| Order / More Info | Phospho-GRK1 (Ser21) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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