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| Antigenic Specificity | PHD3 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | peptide-ELISA: 1:8000, Western Blot: 0.1-0.3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PHD3 Polyclonal Antibody. Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. May play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. Promotes cell death through a caspase-dependent mechanism. |
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| Immunogen | n/a |
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| Other Names | EGLN3 ; egl nine homolog 3 (C. elegans) ; FLJ21620; HIFPH3; MGC125998; MGC125999; PHD3; EGL nine (C.elegans) homolog 3; egl nine homolog 3; egl nine-like protein 3 isoform |
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| Gene, Accession # | Entrez: 112399; Uniprot: Q9H6Z9 |
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| Catalog # | PA5-18957 |
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| Price | |
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| Order / More Info | PHD3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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