产品名称 PHD3 Antibody from INVITROGEN ANTIBODIES
产品货号 A300-327A
产品价格 现货询价,电话:010-67529703
产品规格 100 µL
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityPHD3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size100 µL
Concentrationn/a
ApplicationsWestern Blot: 1:2,000-1:10,000
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPHD3 Polyclonal Antibody. HIF prolyl hydroxylase 3 is a prolyl hydroxylase that modifies HIF-alpha. Classic prolyl hydroxylases are found in the endoplasmic reticulum and modify collagen, whereas HIF is an intracellular protein and the HPH sites do not resemble those modifying collagen. HIF is a transcriptional complex that plays a critical role in oxygen homeostasis. HPH is an essential component of the pathway through which cells sense oxygen. In the presence of oxygen, HPHs convert specific prolyl residues in HIF-alpha to hydroxyproline, leading to HIF-alpha destruction. Low oxygen levels, sensed at the cellular level, cause the HIF conversion to be reduced so that HIF is stable and there is increased angiogenesis. HIF prolyl hydroxylase
Immunogenn/a
Other NamesEGL9 homolog of C. elegans 3, EGLN3, Factor responsive smooth muscle protein, HIF Prolyl Hydroxylase 3, HIFP4H3, HIFPH3, P4H3, Prolyl Hydroxylase Doma
Gene, Accession #Entrez: 112399, 112407; Uniprot: Q91UZ4, Q9H6Z9
Catalog #A300-327A
Price
Order / More InfoPHD3 Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
产品资料