| 产品详情 |
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| Antigenic Specificity | FKBP12 |
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| Clone | 1 HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FKBP12 Antibody (1 HCLC), ABfinity™ Rabbit Oligoclonal. FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. |
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| Immunogen | n/a |
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| Other Names | FKBP1, FKBP12 |
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| Gene, Accession # | Entrez: 14225, 25639; Uniprot: P26883, Q62658 |
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| Catalog # | 711275 |
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| Price | |
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| Order / More Info | FKBP12 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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