产品详情 |
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Antigenic Specificity | TTF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 0.2-1.0 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TTF1 Polyclonal Antibody. Thyroid transcription factor-1 (TTF-1), also known as NK2 homeobox 1(NKX2-1), is a member of the NKx2 family of homeodomain transcription factors. It binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. TTF-1 is important in the maintenance of thyroid differentiation and lung development. It is expressed in epithelial cells of the thyroid gland and the lung, and tumors derived from such epithelial cells. TTF-1 is usually found in primary lung adenocarcinomas, small cell carcinomas and thyroid cancer. It is absent in mesotheliomas, breast cancer and colon cancer. |
Immunogen | n/a |
Other Names | BCH, BHC, NK-2, NKX2.1, NKX2A, TEBP, TITF1, TTF-1, TTF1, NK-2 homolog A, homeobox protein NK-2 homolog A, homeobox protein Nkx-2.1, thyroid nuclear factor 1, thyroid transcription factor 1 |
Gene, Accession # | Entrez: 22130, 499766; Uniprot: Q62187 |
Catalog # | PA5-68792 |
Price | |
Order / More Info | TTF1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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