产品详情 |
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Antigenic Specificity | IRF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ChIP assay: 1:25, Immunoprecipitation: 1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IRF4 Polyclonal Antibody. The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. |
Immunogen | n/a |
Other Names | IRF-4; NF-EM5; lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1 |
Gene, Accession # | Entrez: 3662; Uniprot: Q15306 |
Catalog # | PA5-17580 |
Price | |
Order / More Info | IRF4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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