产品详情 |
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Antigenic Specificity | IRF5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IRF5 Polyclonal Antibody. The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t (6;14) (p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found. |
Immunogen | n/a |
Other Names | Interferon regulatory factor 5, IRF-5, IRF5 |
Gene, Accession # | Entrez: 27056, 296953, 3663; Uniprot: P56477, Q13568 |
Catalog # | PA5-79518 |
Price | |
Order / More Info | IRF5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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