| 产品详情 |
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| Product Name | Chenodeoxycholic acid |
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| Description | Purity >95% by NMR. Cytotoxic hydrophobic primary bile acid. Activator of farnesoid X receptor (FXR), a nuclear receptor that is hepatoprotective and regulates bile acid synthesis (cholesterol 7alpha-hydroxylase (CYP7A1) suppression), conjugation and transport, as well as genes involved in lipid and glucose metabolism and. Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, insulin resistance, hyperlipidemia and atherosclerosis. Inhibitor of 5beta-reductase (AKR1D1). Potent selective inhibitor of DD2 (AKR1C2). Potent inhibitor of 11beta-HSD1 dehydrogenase. Changes tumor cell viability via IL-6 pathway. Anticancer compound. Apoptosis inducer. Immunosuppressive and anti-inflammatory compound. Modulates oxidative stress. Differentiation regulator of mouse embryonic stem cells. Used for dissolution of cholesterol gallstones. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Anthropodeoxycholic acid, CDCA, Chenodiol, Fluibil, Hekbilin, Kebilis, Ulmenide |
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| Gene, Accession, CAS # | CAS: 474-25-9 |
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| Catalog # | LS-H460 |
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| Price | |
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| Order / More Info | Chenodeoxycholic acid from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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