| 产品详情 |
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| Antigenic Specificity | CD22 |
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| Clone | 2D6 (NIMR-6) |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.2 µg/1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD22 Monoclonal Antibody (2D6 (NIMR-6)), PE. CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa. CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes. CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen. Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias. CD22 is also strongly expressed in hairy cell leukemia. CD22 preferentially binds to alpha2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with si |
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| Immunogen | n/a |
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| Other Names | FLJ22814, MGC130020, SIGLEC-2, SIGLEC2, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, CD22 antigen, T-cell surface antigen Leu-14, sialic acid binding Ig-like lectin 2, sialic acid-binding Ig-like lectin 2 |
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| Gene, Accession # | Entrez: 12483; Uniprot: P35329 |
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| Catalog # | MCD2204 |
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| Price | |
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| Order / More Info | CD22 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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