产品详情 |
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Antigenic Specificity | CD22 |
Clone | 2D6 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 1 mL |
Concentration | n/a |
Applications | Flow Cytometry: 1 µg/10^6 cells, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD22 Monoclonal Antibody (2D6), Biotin. CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa. CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes. CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen. Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias. CD22 is also strongly expressed in hairy cell leukemia. CD22 preferentially binds to alpha2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic |
Immunogen | n/a |
Other Names | Lyb-8, Leu-14, BL-CAM |
Gene, Accession # | Entrez: 12483; Uniprot: P35329 |
Catalog # | MA5-28652 |
Price | |
Order / More Info | CD22 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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