| 产品详情 |
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| Antigenic Specificity | BAD |
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| Clone | E.564.7 |
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| Host Species | Rabbit |
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| Reactive Species | bovine, human, mouse, nonhuman primate, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BAD Monoclonal Antibody (E.564.7). The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
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| Immunogen | n/a |
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| Other Names | BCL-X/BCL-2 binding protein; BCL2-antagonist of cell death protein; BCL2-binding component 6; BCL2-binding protein; bcl-2-binding component 6; bcl-2-like protein 8; bcl-XL/Bcl-2-associated death promoter; bcl2 antagonist of cell death; bcl2-L-8 |
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| Gene, Accession # | Entrez: 12015, 572, 615013, 64639; Uniprot: O35147, Q61337, Q92934 |
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| Catalog # | MA5-14800 |
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| Price | |
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| Order / More Info | BAD Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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