| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Aggrecan |
|---|
| Clone | BC-3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | bovine, canine, equine, feline, guinea pig, human, ovine, porcine, rabbit, rat |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA: 1:1000 - 1:5000, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry (Frozen): 1:10 - 1:2000, Immunohistochemistry (Paraffin): 1:10 - 1:2000, Western Blot: 1:500 - 1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Aggrecan Monoclonal Antibody (BC-3). Aggrecan also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1 is a protein that is encoded by the ACAN gene. The encoded protein is an integral part of the extracellular matrix in cartilaginous tissue and it withstands compression in cartilage. The human form of the protein is 2316 amino acids long (~ 250 kDa) and can be expressed in multiple isoforms due to alternative splicing. Aggrecan exhibits a bottlebrush structure, in which chondroitin sulfate and keratan sulfate chains are attached to an extended protein core. The synthesis and degradation of aggrecan are being investigated for their roles in cartilage deterioration during joint injury, disease, |
|---|
| Immunogen | n/a |
|---|
| Other Names | aggrecan, AGC1, CSPG1, MSK16, CSPGCP, Chondroitin sulfate proteoglycan 1, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan core protein 1, SEDK, aggrecan 1, AGCAN, aggrecan core protein, large aggregating proteoglycan, CSPCP |
|---|
| Gene, Accession # | Entrez: 100009079, 100033876, 100731672, 101084542, 176, 280985, 397255, 403828, 443001, 58968; Uniprot: P07897, P13608, P16112, Q28343, Q28670, Q29011 |
|---|
| Catalog # | MA3-16888 |
|---|
| Price | |
|---|
| Order / More Info | Aggrecan Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 21678465, 23710801, 24286485, 26101996, 26744243, 26828861, 27001140, 27090590, 27640363, 28095754 |
|---|
| 产品资料 |
|
|