| 产品详情 |
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| Antigenic Specificity | Aggrecan Neo |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, human, mouse, porcine, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunofluorescence: Assay dependent, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Aggrecan Neo Polyclonal Antibody. Aggrecan is a member of large, aggregating proteoglycans (also including, versican, brevican and neurocan) found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMP's) and aggrecanase (ADAMTS). Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. The C-terminal NITEGE fragment is one of the G1 fragments produced when aggrecan is cleaved with aggrecanase. It is the most abundant fragment found in normal human synovial fluid and articular c |
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| Immunogen | n/a |
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| Other Names | AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK |
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| Gene, Accession # | Entrez: 11595, 176, 280985, 397255, 403828, 58968; Uniprot: P07897, P13608, P16112, Q28343, Q29011, Q61282 |
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| Catalog # | PA1-1746 |
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| Price | |
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| Order / More Info | Aggrecan Neo Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10998358, 11535123, 19526482, 23705804, 26663140, 27640363, 29299344 |
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