| 产品详情 |
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| Antigenic Specificity | LBP |
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| Clone | 1C7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: 1:50, Functional Assay: 1:50, Immunoprecipitation: 1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LBP Monoclonal Antibody (1C7). LPS binding protein (LBP) is an approximately 60 kDa acute phase protein that is produced by hepatocytes. This protein strongly binds to LPS and has been shown to play an important role in the handling of LPS by the host. A number of functions of LBP have been reported. First, LBP transfers LPS to the LPS receptor CD14 on the mononuclear phagocytes, leading to an 100-1,000 fold increased sensitivity of the cells to LPS. Furthermore, LBP can enhance the response of CD14 negitive cells by acceleration of LPS binding to soluble CD14, a complex that stimulates these cells. Next, LBP transfers LPS into High Density Lipoprotein (HDL), which effectively neutralizes its biological potency. LBP was demonstrated to prot |
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| Immunogen | n/a |
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| Other Names | lipopolysaccharide binding protein |
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| Gene, Accession # | Entrez: 3929; Uniprot: P18428 |
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| Catalog # | MA1-40130 |
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| Price | |
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| Order / More Info | LBP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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