产品详情 |
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Antigenic Specificity | BCAR1/p130CAS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:100-1:500, Immunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BCAR1/p130CAS Polyclonal Antibody. The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation. |
Immunogen | n/a |
Other Names | Cas scaffolding protein family member 1; Crk-associated substrate p130Cas; OTTHUMP00000174941; breast cancer anti-estrogen resistance protein 1 |
Gene, Accession # | Entrez: 12927, 9564; Uniprot: P56945, Q61140 |
Catalog # | A301-667A |
Price | |
Order / More Info | BCAR1/p130CAS Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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