产品详情 |
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Antigenic Specificity | RASA3 |
Clone | 1F11 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay-Dependent, Western Blot: 1-5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RASA3 Monoclonal Antibody (1F11). The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma m |
Immunogen | n/a |
Other Names | RP11-245B11.3, GAP1IP4BP, GAPIII, GAP1(IP4BP), GTPase activating protein III, Ins(1,3,4,5)P4-binding protein, inositol 1,3,4,5-tetrakisphosphate-binding protein, ins P4-binding protein, ras GTPase-activating protein 3 |
Gene, Accession # | Entrez: 22821; Uniprot: Q14644 |
Catalog # | MA5-21351 |
Price | |
Order / More Info | RASA3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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