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| Antigenic Specificity | Cul5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 10 µL |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 1:50-1:500, Immunohistochemistry: 1:50-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cul5 Polyclonal Antibody. Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor. |
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| Immunogen | n/a |
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| Other Names | VACM-1; Vasopressin-activated calcium-mobilizing receptor; Cullin-5; CUL-5; CUL5; VACM1 |
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| Gene, Accession # | Entrez: 8065; Uniprot: Q93034 |
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| Catalog # | IHC-00625-T |
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| Price | |
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| Order / More Info | Cul5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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