| 产品详情 |
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| Antigenic Specificity | Cul4B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 20 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:50-1:200, Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cul4B Polyclonal Antibody. Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage. Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA re |
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| Immunogen | n/a |
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| Other Names | MRXHF2, MRXS15, MRXSC, SFM2, CUL-4B, cullin-4B |
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| Gene, Accession # | Entrez: 72584, 8450; Uniprot: A2A432, Q13620 |
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| Catalog # | A303-864A-T |
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| Price | |
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| Order / More Info | Cul4B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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