产品详情 |
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Antigenic Specificity | Cullin 1 |
Clone | 2H4C9 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 0.1-1.0 µg/mL, Immunoprecipitation: 5-10 µg, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cullin 1 Monoclonal Antibody (2H4C9). Cullin 1 is a member of the family of human cullin genes (CUL 1, 2, 3, 4a, 4b, and 5) homologous to the S. cerevisiae cdc 53 gene. CUL 1 forms a complex with human p19 skp1 and F box protein p45 skp2, both of which, together with cdc 53 (known as CUL A), as three subunits form a ubiquitin ligase controlling proteolysis of G1 cell cycle regulatory proteins. The CUL 1/p19 skp1/p45 skp2complex is thought to play a role in the ubiquitination of G1 regulatory proteins. |
Immunogen | n/a |
Other Names | CUL-1, cullin-1 |
Gene, Accession # | Entrez: 26965, 362356, 8454; Uniprot: B1WBY1, Q13616, Q9WTX6 |
Catalog # | 32-2400 |
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Order / More Info | Cullin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 18354482, 21368833, 22219362, 22537386, 23902736, 23936024, 24390425, 25425648, 26631746, 26766115, 27294876, 27317434 |
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