| 产品详情 |
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| Antigenic Specificity | Cullin 2 |
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| Clone | 50H17L12 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5-1 µg/test, Immunocytochemistry: 8-12 µg/mL, Immunofluorescence: 8-12 µg/mL, Immunohistochemistry (Paraffin): 4-6 µg/mL, Western Blot: 3-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cullin 2 Antibody (50H17L12), ABfinity™ Rabbit Monoclonal. In yeast, proteolysis of G1 cell cycle regulatory proteins is controlled by an ubiquitin ligase formed by three subunits: Cdc53 (also known as CulA), Skp1 and one of many F-box proteins. A family of human cullin genes homologous to the S. cerevisiae cdc53 gene has been identified (cul1, 2, 3, 4a, 4b, and 5). In humans Cul2 is part of the ECS (Elongin B/C-Cul2/Cul5-SOCS-box protein) complex which contains the Cullin-RBX module. Human Cul2 does not associate with Skp1 and Skp2. Instead it forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongin C, Elongin B and VHL. The Cul2-Rbx1 module specifically interacts with the VHL box. |
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| Immunogen | n/a |
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| Other Names | CUL-2 |
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| Gene, Accession # | Entrez: 361258, 71745, 8453; Uniprot: Q13617, Q9D4H8 |
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| Catalog # | 700179 |
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| Price | |
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| Order / More Info | Cullin 2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26906416 |
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