| 产品详情 |
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| Antigenic Specificity | DDB1 |
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| Clone | ZD001 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rabbit, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DDB1 Monoclonal Antibody (ZD001). This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. |
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| Immunogen | n/a |
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| Other Names | DDBA, UV-DDB1, XAP1, XPCE, XPE, XPE-BF |
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| Gene, Accession # | Entrez: 100354475, 13194, 1642, 64470; Uniprot: Q16531, Q3U1J4, Q9ESW0 |
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| Catalog # | 39-9901 |
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| Price | |
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| Order / More Info | DDB1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 24699724, 26913219 |
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| 产品资料 |
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