| 产品详情 |
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| Antigenic Specificity | DDB2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DDB2 Polyclonal Antibody. Damaged DNA binding protein (DDB) is a heterodimer composed of two subunits, p127 and p48, which are designated DDB1 and DDB2, respectively. The DDB heterodimer is involved in repairing DNA damaged by ultraviolet light. Specifically, DDB, also designated UV-damaged DNA binding protein (UV-DDB), xeroderma pigmentosum group E binding factor (XPE-BF) and hepatitis B virus X-associated protein 1 (XAP-1), binds to damaged cyclobutane pyrimidine dimers (CPDs). Mutations in the DDB2 gene are implicated as causes of xeroderma pigmentosum group E, an autosomal recessive disease in which patients are defective in nucleotide excision DNA repair. XPE is characterized by hypersensitivity of the skin to sunlight with a high freq |
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| Immunogen | n/a |
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| Other Names | damage-specific DNA binding protein 2, UV-DDB 2 |
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| Gene, Accession # | Entrez: 100362121, 107986, 1643; Uniprot: Q92466, Q99J79 |
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| Catalog # | PA5-37361 |
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| Price | |
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| Order / More Info | DDB2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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