产品详情 |
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Antigenic Specificity | GluR5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 0.5-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GluR5 Polyclonal Antibody. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. |
Immunogen | n/a |
Other Names | EAA3, EEA3, GLR5, GLUR5; excitatory amino acid receptor 3; gluR-5; glutamate receptor 5; glutamate receptor, ionotropic kainate 1 |
Gene, Accession # | Entrez: 14805, 2897, 29559; Uniprot: P22756, P39086, Q60934 |
Catalog # | PA5-20448 |
Price | |
Order / More Info | GluR5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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