| 产品详情 |
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| Antigenic Specificity | GLUT4 |
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| Clone | 1F8 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate, porcine, rabbit, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Immunofluorescence: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GLUT4 Monoclonal Antibody (1F8). The stimulation of glucose uptake by insulin in muscle and adipose tissue requires translocation of the GLUT4 (Glucose transporter type 4, insulin-responsive) glucose transporter from intracellular storage sites to the cell surface. Insulin stimulates glucose transport by promoting translocation of GLUT4 proteins from the perinuclear compartment to the cell surface. Human insulin resistance involves a defect in GLUT4 traffic and targeting leading to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface. |
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| Immunogen | n/a |
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| Other Names | Glut4, MGC93607 |
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| Gene, Accession # | Entrez: 100037710, 20528, 25139, 396754, 6517; Uniprot: P14142, P14672, P19357, Q9XT10 |
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| Catalog # | MA1-83191 |
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| Price | |
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| Order / More Info | GLUT4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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