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Antigenic Specificity | Glutamate Dehydrogenase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Western Blot: 1:100 - 1:250 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glutamate Dehydrogenase Polyclonal Antibody. This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans. |
Immunogen | n/a |
Other Names | GLUD1; glutamate dehydrogenase 1; GDH; GDH1; GLUD; MGC132003; glutamate dehydrogenase (NAD(P)+); GLUD2; glutamate dehydrogenase 2; GDH2; GLUDP1; glutamate dehydrogenase pseudogene 1 |
Gene, Accession # | Entrez: 2746; Uniprot: P00367 |
Catalog # | PA5-66382 |
Price | |
Order / More Info | Glutamate Dehydrogenase Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |