| 产品详情 |
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| Antigenic Specificity | NRGN |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 4-6 µg/mL, Immunohistochemistry: 5 µg/mL, peptide-ELISA: 1:8000, Western Blot: 0.1-0.3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NRGN Polyclonal Antibody. Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. |
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| Immunogen | n/a |
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| Other Names | NRGN; neurogranin (protein kinase C substrate, RC3); RC3; hng; calmodulin-binding protein; neurogranin; protein kinase C substrate |
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| Gene, Accession # | Entrez: 4900, 64011, 64356; Uniprot: P60761, Q04940, Q92686 |
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| Catalog # | PA5-19209 |
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| Price | |
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| Order / More Info | NRGN Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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