| 产品详情 |
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| Antigenic Specificity | 53BP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ChIP assay: Assay-Dependent, Immunocytochemistry: 1:50-1:1000, Immunofluorescence: 1:50-1:1000, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:10-1:500, Western Blot: 1:2000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | 53BP1 Polyclonal Antibody. 53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability. |
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| Immunogen | n/a |
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| Other Names | TP53BP1, p202 |
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| Gene, Accession # | Entrez: 27223, 296099, 7158; Uniprot: P70399, Q12888 |
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| Catalog # | PA1-16566 |
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| Price | |
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| Order / More Info | 53BP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 22936983, 27565756 |
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| 产品资料 |
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