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| Antigenic Specificity | SIPA1L3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1,000-1:5,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SIPA1L3 Polyclonal Antibody. Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation. |
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| Immunogen | n/a |
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| Other Names | SPAL3; SIPA1-like protein 3; SPA-1-like 3; SPA-1-like protein 3; signal-induced proliferation-associated 1-like protein 3 |
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| Gene, Accession # | Entrez: 23094; Uniprot: O60292 |
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| Catalog # | A304-155A |
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| Price | |
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| Order / More Info | SIPA1L3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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