产品详情 |
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Antigenic Specificity | SIRP alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIRP alpha Polyclonal Antibody. The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its |
Immunogen | n/a |
Other Names | BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP, CD172 antigen-like family member A, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, inhibitory receptor SHPS-1, macrophage fusion receptor, myd-1 antigen, tyrosine phosphatase SHP substrate 1, tyrosine-protein phosphatase non-receptor |
Gene, Accession # | Entrez: 140885, 19261; Uniprot: P78324, P97797 |
Catalog # | PA5-29544 |
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Order / More Info | SIRP alpha Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 28383029 |
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