产品详情 |
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Antigenic Specificity | SIRP alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 1 µg/mL, Western Blot: 0.5-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIRP alpha Polyclonal Antibody. Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPalpha, SHPS-1, MyD-1, BIT and p84. SIRPalpha is a new gene family containing at least fifteen members. SIRPalpha is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2. SIRPalpha has |
Immunogen | n/a |
Other Names | BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP; CD172 antigen-like family member A; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; inhibitory receptor SHPS-1; macrophage fusion receptor; myd-1 antigen; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1 |
Gene, Accession # | Entrez: 140885, 19261, 25528; Uniprot: P78324, P97710, P97797 |
Catalog # | PA5-19869 |
Price | |
Order / More Info | SIRP alpha Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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