| 产品详情 |
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| Antigenic Specificity | SIRT2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:400, Immunofluorescence: 1:400, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:250 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SIRT2 Polyclonal Antibody. The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair. It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells. SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise. SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis. |
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| Immunogen | n/a |
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| Other Names | Sirtuin for Silent Mating Type Information 2-Homolog |
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| Gene, Accession # | Entrez: 22933, 361532, 64383; Uniprot: Q5RJQ4, Q8IXJ6, Q8VDQ8 |
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| Catalog # | PA3-200 |
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| Price | |
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| Order / More Info | SIRT2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18694573, 18696335, 18697214, 23908241 |
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