| 产品详情 |
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| Antigenic Specificity | SIRT5 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | biotin conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 0.5 mg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SIRT5 Monoclonal Antibody, Biotin. SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-ly |
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| Immunogen | n/a |
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| Other Names | SIR2L5, NAD-dependent deacetylase sirtuin-5, SIR2-like protein 5, silent mating type information regulation 2, S.cerevisiae, homolog 5, sir2-like 5, sirtuin type 5 |
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| Gene, Accession # | Entrez: 23408; Uniprot: Q9NXA8 |
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| Catalog # | 730092 |
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| Price | |
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| Order / More Info | SIRT5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26121405 |
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