产品详情 |
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Antigenic Specificity | SIRT5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIRT5 Polyclonal Antibody. SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine gro |
Immunogen | n/a |
Other Names | FLJ36950, SIR2L5 |
Gene, Accession # | Entrez: 23408, 306840, 68346; Uniprot: Q68FX9, Q8K2C6, Q9NXA8 |
Catalog # | PA1-41129 |
Price | |
Order / More Info | SIRT5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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