| 产品详情 |
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| Antigenic Specificity | CD45RB |
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| Clone | MEM55 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 200 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:50-1:100 (10 µL for 10^6 cells in 100 µL), Immunohistochemistry (Frozen): Assay dependent, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: Assay dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD45RB Monoclonal Antibody (MEM55). CD45RB is a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed in microglia and inflammatory cells. In addition to invol |
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| Immunogen | n/a |
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| Other Names | B220, CD45, CD45R, GP180, LCA, LY5, T200 |
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| Gene, Accession # | Entrez: 5788; Uniprot: P08575 |
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| Catalog # | MA1-90840 |
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| Price | |
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| Order / More Info | CD45RB Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12858435 |
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| 产品资料 |
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