产品详情 |
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Antigenic Specificity | CD45RC |
Clone | MIL5 |
Host Species | Mouse |
Reactive Species | porcine |
Isotype | IgG1 |
Format | purified |
Size | 2 mL |
Concentration | n/a |
Applications | Flow Cytometry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45RC Monoclonal Antibody (MIL5). CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 100522631 |
Catalog # | MA5-28401 |
Price | |
Order / More Info | CD45RC Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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